Lymphoma takes the form of tumors in the lymph system that are made up of cancerous lymphocytes. Lymphoma differs from lymphocytic leukemia, which consists of immature cancerous lymphocytes floating in the bloodstream.
CBD kills lymphoma cells[Massi_2012].
Linalool is cytotoxic against human lymphoma cell
lines[Chiang]. β-Caryophyllene and caryophyllene oxide induce apoptosis in human lymphoma cells[Naog_2014].
α-Pinene is cytotoxic against histiocytic lymphoma[Sobra_2014].
d-Limonene inhibits the proliferation of murine lymphoma[Manu_2008].
Elevated IL-10 plasma levels correlate with poor prognosis in patients with diffuse large B-cell lymphoma[Lech-Maranda_2006].
IL-10 provides resistance to cytotoxic drugs in Non-Hodgkin’s Lymphoma by blocking apoptosis[Alas_2001].
IL-1α and IL-8 immunoreactivity are increased in patients with cutaneous T-cell lymphoma[Hansen_1991].
Beta caryophyllene and caryophyllene oxide are potent anti-inflammatory agents against lymphoma cells[Sain_2014].
Taming Inflammatory Cytokines
has some additional ideas on lowering inflammatory cytokines.
Chiang. Antileukemic Activity of Selected Natural Products in Taiwan. Abstract. Chiang L-C, Chiang W, Chang M-Y, et al. The American Journal of Chinese Medicine. Undated.
Naog_2014. Beta caryophyllene and caryophyllene oxide, isolated from Aegle marmelos, as the potent anti-inflammatory agents against lymphoma and neuroblastoma cells. Abstract. Sain S, Naoghare P K, Devi S S, et al. Anti-inflammatory & anti-allergy agents in medicinal chemistry. Published 2014 March.
Massi_2012. CBD and leukaemia/lymphoma [in Cannabidiol as potential anticancer drug]. Summary. Massi P, Solinas M, Cinquina C, Parolaro D. British Pharmacological Society. Online 2012 April 17.
Sain_2014. Beta caryophyllene and caryophyllene oxide, isolated from Aegle marmelos, as the potent anti-inflammatory agents against lymphoma and neuroblastoma cells. Abstract. Sain S, Naoghare P K, Devi S S, et al. Anti-inflammatory & anti-allergy agents in medicinal chemistry. Published 2014 March.
Manu_2008. Effect of Tilia x viridis flower extract on the proliferation of a lymphoma cell line and on normal murine lymphocytes: contribution of monoterpenes, especially limonene. Abstract. Gabriela Manuele M G, Ferraro G, Anesini C. Phytotherapy research. Published 2008 November.
Sobra_2014. 1.25\. Alpha- and Beta-Pinene [in Antitumor Activity of Monoterpenes Found in Essential Oils]. Summary. Sobral M, Xavier A L, Lima T C, de Sousa D P. ScientificWorldJournal. Online 2014 October 14.
Lech-Maranda_2006. Elevated IL-10 plasma levels correlate with poor prognosis in diffuse large B-cell lymphoma. Abstract. Lech-Maranda E, Bienvenu J, Michallet A-S, et al. European cytokine network. Published 2006 March.
Alas_2001. Inhibition of Interleukin 10 by Rituximab Results in Down-Regulation of Bcl-2 and Sensitization of B-cell Non-Hodgkin’s Lymphoma to Apoptosis. Full text. Alas S, Emmanouilides C, Bonavida B. Clinical Cancer Research. March 2001.
Hansen_1991. Epidermal interleukin 1 alpha functional activity and
interleukin 8 immunoreactivity are increased in patients with cutaneous
Abstract. Hansen E R, Vejlsgaard G L, Lisby S, et al. The Journal of
investigative dermatology. 1991 November.